CANDOR launches key component for better serological assays (Antibody Tests) for Covid-19.
As the Covid-19 pandemic is critical for all of us, we need to have the best diagnostic tools to face this challenge.
Antibody tests can show whether a person is immune against Covid-19 or not. This is important, because if a person is immune (after experiencing the infection with or without symptoms or hopefully later after successful vaccination in the future), immune health workers will work without risk of Covid-19 re-infection for themselves and the risk of spreading the virus unknowingly to others in critical functions such as the NHS and social care. This testing could then be used to issuing an immunity 'passport' also for key workers in public services such as police, military and many others.
However, if such Covid-19 immunoassays (Antibody Tests) show false-positives, a person could erroneously be considered as immune. If the individual afterwards becomes infected in an asymptomatic way, they could spread this perfidious virus widely. So, false-positives in an immunoassay bear the risk to generate super-spreaders.
Thus, correct results in immunoassays are important as ever for all of us, worldwide.
The team at CANDOR Bioscience, Germany have developed and tested options to enable for the development of very reliable, professional SARS-CoV-2 immunity ELISAs.
Their findings show that a combination of CANDOR's new serological surface blocker PlateBlockTM, the well-established assay diluent for avoiding cross-reactivities and interference LowCross-Buffer®, the coating stabilizer Liquid Plate Sealer® and the conjugate stabilizer LowCross® HRP-Stab.
Published in a recent White Paper, CANDOR describes how their products, including the new PlateBlockTM can help to design, develop and manufacturer high quality Covid-19 antibody tests for routine laboratory use (in vitro diagnostic assays, ELISA):
CoViD-19-antibody-test-challenge NEW
Another short article describes the reason why during a pandemic even an assay showing 99% specificity is far too inferior to be used as a reliable screening assays, which is strongly needed now.
Specificity, positive predictive value and validation statistics in the context of CoViD-19 NEW
Check out the anti-Covid-19 immunoassay tool box section from BIOAXXESS UK here.
Learn more about CANDOR's newly launched
#163 Liquid Plate Sealer® animal-free
Coating Stabilizer without animal derived ingredients for antibodies and antigens coated on polystyrene- or glass-surfaces
Liquid Plate Sealer® animal-free offers the same excellent stabilizing characteristics as Liquid Plate Sealer® but without having animal derived ingredients.
This makes Liquid Plate Sealer® animal-free suitable coating stabilizer for veterinary diagnostics.
Just add Liquid Plate Sealer® animal-free directly without any washing steps to the plates after the coating process has been completed: simplify and speed up your production process.
Learn more about CANDOR's launched
All-in-One Solution for Western blotting from CANDOR Bioscience:
now also available for use with polyclonal antibodies from Rabbit available in the UK from BIOAXXESS.
Claim your Anti-Rabbit-HRP ReadyTector Trial Kit for FREE with your next order of CANDOR products from BIOAXXESS!
Change of ProClin® 300 Concentration in CANDOR Products
Starting 1st of June 2015 the next „level“ of CLP Regulation 1272/2008 for mixtures comes into full effect (Regulation on classification, labelling and packaging of substances and mixtures).
This results in new rules for the classification of potential chemical hazards.
CANDOR Bioscience uses in most solutions the preservative ProClin® 300 which has been used in a concentration of 0.1 % (v/v) to avoid microbial growth.
Starting from 1st June 2015 we produce such solutions with the same preservative in a concentration of 0.045 % (v/v). Therefore no hazard labelling will be necessary for the solutions.
The manufacturer of ProClin® 300 recommends using it in the concentration range of 0.03 % up to 0.05 % (v/v) to prevent microbial growth. Thus we use the preservative still in the upper range of the recommendation of the manufacturer.
As the air-borne load of microbial contaminants differs significantly from laboratory to laboratory, we generally recommend working as cleanly as possible, when opening the bottles for decanting and re-storing the remaining solutions until next use. With clean and proper use there is no risk of microbial growth to be expected even if the guaranteed and stated shelf-life is only valid for an un-opened bottle. If you still fear contamination it may be beneficial to add additional preservatives or antibiotics for a longer shelf-life.