PlateBlock™ Cat. No. #112
PlateBlock™ is an animal-free and protein-free blocker for plastic surfaces (e.g. microtiter plates). This blocker is optimized for serological assays (antigen-down-assays).
For this assay format, it is essential that the blocking does not cover the epitope of the capture antigen and that the detector antibody does not cross react with the blocking surface.
In addition, some serum and plasma specimens from patients tend to detach single molecules from the dense blocking layer and replace them with other molecules (mostly antibodies of the patients). This results in high background levels if the specimen is not highly diluted. (Antibodies in low concentration could not be detected if the dilution of the sample is too high). Additionally, cross-linking between blocking and detector antibodies can be initiated by serum proteins.
See Fig. 4 on PlateBlockTM compared to other ELISA plate blockers as taken from CANDOR's White Paper 'Covid-19 Antibody Test Challenge'.
PlateBlock™ is optimized to effectively prevent these kinds of substitution and background effects.
PlateBlock™ is ready-to use and available in bottle sizes of 125 mL and 500 mL.
For research use only, not for diagnostic use.
Please note that the 1 L size will be packaged in 2x 500 ml bottles.
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